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Master Obstetrics and Gynecology
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HIGH YIELD NOTES ~5 min read

Core Concepts

Obstetrics and Gynecology (ObGyn) encompasses female reproductive health, pregnancy, childbirth, and puerperium. It combines medical and surgical management. Key principles include understanding normal physiological changes (menstrual cycle, pregnancy), early detection and management of complications, and preventative care (e.g., vaccination, screening). Emphasis is placed on maternal and fetal well-being, contraception, fertility, and management of gynecological pathologies across all ages.

Clinical Presentation

  • Abnormal Vaginal Bleeding:
    • Antepartum: Painless (Placenta Previa), Painful (Abruptio Placentae).
    • Postpartum: Heavy bleeding after delivery (Postpartum Hemorrhage - PPH).
    • Non-gravid: Menorrhagia, metrorrhagia, post-coital, post-menopausal (e.g., endometrial pathology, fibroids, polyps, cervical cancer).
  • Pelvic Pain: Acute (e.g., Ectopic pregnancy, PID, ovarian torsion, ruptured cyst) or Chronic (e.g., Endometriosis, Adenomyosis, adhesions).
  • Vaginal Discharge: Itchiness, odor, dysuria (e.g., Infections like Candidiasis, Bacterial Vaginosis, STIs).
  • Pregnancy-related Symptoms: Nausea/vomiting, hypertension (e.g., Pre-eclampsia), reduced fetal movement, preterm contractions, symptoms of DVT/PE.
  • Infertility: Inability to conceive after 12 months (or 6 months if >35 years) of unprotected intercourse.
  • Urinary Symptoms: Frequency, urgency, incontinence (e.g., UTI, pelvic organ prolapse).

Diagnosis (Gold Standard)

  • Pregnancy Confirmation: Serum/urine hCG.
  • Ectopic Pregnancy: Transvaginal Ultrasound (TVS) showing extrauterine gestational sac + hCG levels not doubling appropriately.
  • Gestational Diabetes Mellitus (GDM): Oral Glucose Tolerance Test (OGTT) at 24-28 weeks.
  • Pre-eclampsia: New-onset hypertension (>140/90 mmHg after 20 weeks) with proteinuria or end-organ dysfunction.
  • Placenta Previa/Abruptio Placentae: Transabdominal Ultrasound (for previa), clinical presentation (for abruption).
  • Cervical Cancer Screening: Pap smear (cytology) followed by colposcopy with biopsy for abnormal results.
  • Endometrial Cancer: Endometrial biopsy.
  • Ovarian Mass: Pelvic Ultrasound; CA-125 for suspicion of malignancy.
  • Pelvic Inflammatory Disease (PID): Clinical diagnosis (pelvic pain, cervical motion tenderness, adnexal tenderness, fever, discharge); definitive with laparoscopy.
  • Infertility: Comprehensive workup including semen analysis, ovulation assessment (progesterone), tubal patency (HSG), ovarian reserve (AMH, FSH).

Management (First Line)

  • Antenatal Care: Regular visits, screening (blood group, infections, GDM), nutritional advice, folic acid.
  • Pre-eclampsia: Delivery is definitive management; Magnesium Sulfate for seizure prophylaxis/eclampsia treatment; Antihypertensives (Labetalol, Nifedipine, Hydralazine).
  • Postpartum Hemorrhage (PPH): Uterine massage, Oxytocin; explore causes (tone, trauma, tissue, thrombin).
  • Ectopic Pregnancy:
    • Stable: Methotrexate (IM).
    • Unstable/Contraindication to MTX: Surgical (laparoscopic salpingectomy).
  • Gestational Diabetes: Dietary modifications, exercise; Insulin if diet/exercise fail.
  • Preterm Labor: Tocolytics (Nifedipine, Indomethacin), Betamethasone (fetal lung maturity), antibiotics for PROM.
  • Cervical Intraepithelial Neoplasia (CIN): LEEP (Loop Electrosurgical Excision Procedure) or cryotherapy.
  • Pelvic Inflammatory Disease (PID): Broad-spectrum antibiotics (e.g., Ceftriaxone + Doxycycline + Metronidazole).
  • Menorrhagia (Heavy Menstrual Bleeding): Tranexamic acid, NSAIDs, hormonal contraceptives (COCs), Mirena IUD.
  • Contraception: Discuss options based on patient needs/contraindications (COCs, Progestin-only, IUD, implant, barrier methods).

Exam Red Flags

  • Acute severe abdominal pain in pregnancy: Ectopic rupture, Abruptio Placentae, Uterine rupture.
  • Vaginal bleeding in 3rd trimester: Placenta Previa (painless) or Abruptio Placentae (painful).
  • New-onset hypertension with headache/visual changes/epigastric pain in pregnancy: Severe Pre-eclampsia/HELLP Syndrome.
  • Reduced fetal movement at term: Fetal distress, requiring urgent assessment (NST, BPP).
  • Post-menopausal bleeding: Endometrial cancer until proven otherwise (requires endometrial biopsy).
  • Hemodynamic instability (tachycardia, hypotension) in any ObGyn context: Indicates significant blood loss (e.g., PPH, ruptured ectopic) or sepsis, requires immediate resuscitation.
  • Shoulder Dystocia/Cord Prolapse during labor: Obstetric emergencies requiring immediate action.

Sample Practice Questions

Question 1

A 35-year-old Saudi woman presents for her routine health check-up. She is asymptomatic and has no history of abnormal Pap smears. Her last Pap smear was performed at age 30 and was reported as normal. She has been sexually active for 15 years and reports having received the HPV vaccine during her early twenties.

A) Repeat Pap smear alone every 3 years.
B) Perform HPV testing alone every 5 years.
C) Perform co-testing (Pap smear + HPV testing) every 5 years.
D) No further cervical cancer screening is needed due to HPV vaccination and previous normal Pap smear.
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Question 2

A 36-year-old primigravida at 36 weeks gestation presents with a 2-day history of persistent headache and new-onset visual disturbances. Her blood pressure is 160/110 mmHg, and urine dipstick shows 3+ proteinuria. Deep tendon reflexes are hyperactive. What is the most appropriate initial management step?

A) Initiate intravenous labetalol for blood pressure control.
B) Administer intravenous magnesium sulfate for seizure prophylaxis.
C) Induce labor immediately.
D) Perform a computed tomography (CT) scan of the brain.
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Question 3

A 35-year-old G3P2 woman seeks contraception. She is breastfeeding her 3-month-old infant and reports a history of migraines with aura. She desires a highly effective, long-acting method. Which of the following contraceptive methods is MOST appropriate for her?

A) Combined Oral Contraceptives (COCs).
B) Progestin-only pills (POPs).
C) Copper Intrauterine Device (IUD).
D) Depot Medroxyprogesterone Acetate (DMPA) injection.
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