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Master General Surgery
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HIGH YIELD NOTES ~5 min read

Core Concepts

  • **Scope:** Diagnosis & management of diseases involving the GI tract (esophagus to rectum), endocrine glands (thyroid, parathyroid, adrenal, pancreas), breast, soft tissues, vascular system, and acute surgical conditions (trauma, critical care).
  • **Key Principles:**
    • **Acute vs. Elective:** Differentiate urgent surgical emergencies from planned procedures.
    • **Sterile Technique:** Fundamental for preventing surgical site infections.
    • **Pre-operative Assessment:** Optimize patient health to minimize risks (cardiac, pulmonary, renal, nutrition, NPO, DVT/antibiotic prophylaxis).
    • **Post-operative Care:** Pain management, fluid balance, early mobilization, monitoring for complications (bleeding, infection, DVT/PE, ileus, anastomotic leak).
    • **Shock & Resuscitation:** Recognize and manage hypovolemic, septic, cardiogenic, obstructive shock (ATLS principles for trauma).

Clinical Presentation

  • **Acute Abdomen:** Sudden severe abdominal pain.
    • **Appendicitis:** Periumbilical pain migrating to RIF, anorexia, N/V, fever, McBurney's tenderness.
    • **Acute Cholecystitis:** RUQ pain radiating to R shoulder/back, fever, N/V, positive Murphy's sign.
    • **Diverticulitis:** LLQ pain, fever, altered bowel habits (often elderly).
    • **Small Bowel Obstruction (SBO):** Colicky pain, vomiting, distension, absolute constipation, tinkling bowel sounds.
    • **Perforated Viscus (e.g., Peptic Ulcer):** Sudden, severe, generalized abdominal pain, guarding, "board-like" rigidity.
    • **Acute Pancreatitis:** Severe epigastric pain radiating to back, N/V.
    • **Ruptured AAA:** Sudden severe back/abdominal pain, hypotension, pulsatile abdominal mass.
  • **Gastrointestinal Bleeding:** Hematemesis/melena (UGI), hematochezia (LGI).
  • **Hernias:** Palpable bulge; pain, irreducibility, or strangulation signs (erythema, systemic toxicity) are critical.
  • **Breast Lumps:** Palpable mass, skin changes (peau d'orange), nipple discharge/retraction.
  • **Thyroid Pathology:** Neck lump/swelling (goiter), dysphagia, dyspnea, hoarseness, +/- hypo/hyperthyroid symptoms.
  • **Trauma:** Injuries following blunt/penetrating force; focus on ABCDE assessment.
  • **Surgical Infections:** Localized pain, swelling, redness, warmth, fever (e.g., abscesses, cellulitis, necrotizing fasciitis).
  • **Vascular:**
    • **Peripheral Arterial Disease (PAD):** Intermittent claudication, rest pain, trophic changes, non-healing ulcers.
    • **Deep Vein Thrombosis (DVT):** Leg pain, swelling, tenderness, warmth, erythema.

Diagnosis (Gold Standard)

  • **History & Physical Examination:** Always the first and most crucial step.
  • **Laboratory Tests:** CBC (leukocytosis, anemia), U&E, LFT, Amylase/Lipase, Coagulation profile, G&S, ABG.
  • **Imaging:**
    • **Plain Radiographs (CXR/AXR):** CXR: free air under diaphragm (perforation). AXR: dilated bowel loops, air-fluid levels (SBO).
    • **Ultrasound (US):** Highly useful for gallstones/cholecystitis, appendicitis (peds/pregnant), AAA, DVT, breast lumps, thyroid nodules.
    • **Computed Tomography (CT) Scan:** **Often gold standard for acute abdomen** (appendicitis, diverticulitis, perforation, AAA, trauma assessment, staging malignancy). CT angiography for vascular disease.
    • **Endoscopy (EGD/Colonoscopy):** Gold standard for diagnosing and often treating GI bleeding, strictures, masses.
    • **Biopsy (Histopathology):** **Definitive for malignancy** (breast, thyroid, GI masses).
    • **Angiography:** Gold standard for vascular lesions (PAD, acute ischemia).

Management (First Line)

  • **Resuscitation & Stabilization:**
    • **ABCDE Assessment:** Prioritize airway, breathing, circulation.
    • **IV Fluids:** Crystalloids (e.g., Normal Saline, Ringer's Lactate) for hypovolemia/shock.
    • **Oxygen:** Supplemental O2 for hypoxia.
    • **Analgesia:** Early pain control (e.g., opioids).
    • **NPO & Nasogastric Tube (NGT):** For bowel obstruction, pancreatitis, pre-op.
  • **Antibiotics:** Empiric broad-spectrum for suspected infection (e.g., intra-abdominal sepsis, diverticulitis, cholecystitis) or prophylaxis.
  • **Specific Surgical Interventions:**
    • **Acute Appendicitis/Cholecystitis:** Laparoscopic appendectomy/cholecystectomy.
    • **Perforated Viscus:** Emergency exploratory laparotomy with primary repair or resection.
    • **Small Bowel Obstruction (SBO):** Initial conservative management (NPO, NGT, IV fluids); surgical lysis of adhesions or resection for strangulation/failure of conservative Rx.
    • **Hernia:** Elective repair (herniorrhaphy/hernioplasty); emergency repair for incarcerated/strangulated hernias.
    • **GI Bleeding:** Endoscopic intervention (clipping, coagulation) often first line; surgical exploration for refractory bleeding.
    • **Breast/Thyroid Cancer:** Surgical resection (mastectomy/thyroidectomy) + adjuvant therapy.
    • **Trauma:** Damage control surgery for severe trauma, specific repairs based on injury.
    • **Abscess:** Incision and drainage (I&D).
    • **PAD:** Revascularization (angioplasty/stenting, bypass surgery) for critical limb ischemia.
    • **DVT:** Anticoagulation (heparin followed by warfarin/DOACs).

Exam Red Flags

  • **Peritonitis (Generalized Rigidity, Rebound Tenderness):** Suggests diffuse intra-abdominal inflammation/perforation, requires urgent surgical exploration.
  • **Hemodynamic Instability/Shock:** Hypotension, tachycardia, altered mental status, indicates severe pathology (e.g., hemorrhage, sepsis) requiring immediate resuscitation and likely surgery.
  • **Strangulated Hernia:** Painful, irreducible hernia with skin changes and systemic toxicity (fever, leukocytosis). **Surgical emergency** due to bowel ischemia.
  • **Necrotizing Soft Tissue Infection (e.g., Necrotizing Fasciitis):** Severe pain out of proportion to exam, rapidly spreading erythema, crepitus, systemic toxicity. Requires **urgent radical debridement**.
  • **Acute Limb Ischemia:** Sudden onset of "6 Ps": Pain, Pallor, Pulselessness, Paresthesia, Paralysis, Poikilothermia. **Surgical emergency** to prevent limb loss.
  • **Ruptured Abdominal Aortic Aneurysm (AAA):** Sudden severe abdominal/back pain, pulsatile mass, hypotension. **Life-threatening emergency**, requires immediate transport to OR.
  • **Septic Shock unresponsive to initial resuscitation:** Indicates ongoing source of infection that needs surgical control (drainage, debridement, resection).

Sample Practice Questions

Question 1

A 45-year-old female presents for evaluation of a newly discovered, painless lump in her left breast. On clinical examination, the lump is 2 cm, firm, irregular, and fixed to the underlying tissue. There is no nipple discharge or axillary lymphadenopathy. She has no family history of breast cancer. What is the most appropriate next diagnostic step?

A) Reassurance and observation for 3-6 months
B) Mammogram only
C) Fine Needle Aspiration (FNA) of the lump
D) Triple Assessment (clinical examination, imaging, and biopsy)
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Question 2

A 68-year-old male with a known history of a reducible right inguinal hernia presents to the emergency department with acute onset of severe pain in his right groin, associated with nausea and vomiting. On examination, there is a tender, firm, non-reducible mass in the right inguinal region. The overlying skin is erythematous and warm. He is tachycardic (HR 110 bpm) and afebrile.

A) Incarcerated hernia without strangulation
B) Strangulated hernia
C) Recurrent inguinal hernia
D) Femoral hernia
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Question 3

A 25-year-old male presents to the emergency department with a 12-hour history of dull periumbilical pain that has now migrated and localized to the right lower quadrant. He reports anorexia and a single episode of nausea. On examination, his temperature is 38.5ยฐC, heart rate 98 bpm, and he exhibits guarding and rebound tenderness in the right iliac fossa. Laboratory tests show a white blood cell count of 15,000 cells/ยตL with neutrophilia. What is the most appropriate next step in the management of this patient?

A) Initiate broad-spectrum intravenous antibiotics and observe for 24 hours.
B) Request an urgent abdominal CT scan to confirm the diagnosis.
C) Perform immediate diagnostic laparoscopy with a readiness for appendectomy.
D) Administer parenteral analgesia and discharge home with instructions to return if symptoms worsen.
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